:root{--navy:#131e3c;--ink:#1b2744;--muted:#66748b;--line:#e1e6ef;--paper:#f4f6fb;--blue:#386bdd;--teal:#078775;--pink:#bc417d;--orange:#bd6621}*{box-sizing:border-box}body{margin:0;background:var(--paper);font-family:Inter,Arial,sans-serif;color:var(--ink);font-size:16px;line-height:1.5}button,input,select{font:inherit}button,a,input,select{outline-offset:4px}button{cursor:pointer}a{color:var(--blue)}.sidebar{position:fixed;inset:0 auto 0 0;width:244px;background:var(--navy);color:white;padding:32px 20px;display:flex;flex-direction:column}.brand{display:flex;gap:12px;align-items:center;color:white;text-decoration:none;font-size:29px;font-weight:750;letter-spacing:-1px}.brandmark{display:grid;place-items:center;width:42px;height:46px;background:#25385d;border-radius:9px;border:1px solid #49607e;color:#72e0cf;font-size:28px}.brand small{display:block;font-size:10px;letter-spacing:1.3px;font-weight:500;color:#9eafcd}.navlabel{margin:52px 12px 13px;color:#91a0bf;font-size:12px;letter-spacing:1.5px}nav button{display:flex;align-items:center;gap:12px;width:100%;border:0;color:#bdc8dd;background:none;padding:13px 12px;border-radius:7px;margin:5px 0;text-align:left;font-size:14px}nav button.active{background:#2a3a5c;color:white;box-shadow:inset 3px 0 #75ddd0}nav button:hover{background:#253456}nav button span{font-size:21px;width:22px}nav b{margin-left:auto;color:#93a6c7;font-size:12px;font-weight:400}.sidebar-bottom{margin-top:auto;padding:24px 12px 0;border-top:1px solid #33405e}.edition{font-size:11px;letter-spacing:1.8px;color:#7ddcce}.sidebar-bottom p{font-size:23px;line-height:1.3;letter-spacing:-.5px}.sidebar-bottom small{display:block;color:#92a2bf;font-size:12px;margin-top:25px}.dimension-key{display:grid;grid-template-columns:8px auto;gap:8px;font-size:12px;color:#aebbd3}.dimension-key i{width:6px;height:6px;background:#799fff;border-radius:50%;margin-top:6px}.dimension-key i:nth-of-type(2){background:#d784b0}.dimension-key i:nth-of-type(3){background:#e9ac72}.page{margin-left:244px}.topbar{height:74px;border-bottom:1px solid var(--line);display:flex;align-items:center;justify-content:space-between;padding:0 38px;background:white;font-size:14px;color:var(--muted)}.topbar strong{color:var(--ink);font-weight:500}.slash{margin:0 13px;color:#bbc3d0}.topnote{font-size:12px;letter-spacing:.5px}main{max-width:1600px;margin:auto;padding:34px 38px 50px}.eyebrow{text-transform:uppercase;letter-spacing:1.7px;font-size:12px;font-weight:700;color:var(--teal);margin:0 0 9px}.heading{display:flex;justify-content:space-between;align-items:center;gap:20px;margin-bottom:25px}h1{font-size:32px;letter-spacing:-1.1px;line-height:1.2;margin:0 0 8px}h2{font-size:19px;letter-spacing:-.4px;margin:0}h3{font-size:16px;margin:0}p{margin:8px 0}.subtitle{color:var(--muted);font-size:15px;max-width:770px}.badge{display:inline-flex;border-radius:5px;background:#edf3ff;color:#3866b0;border:1px solid #d8e6fc;padding:5px 9px;font-size:12px;white-space:nowrap}.badge.co{background:#fff0f6;border-color:#f0ccdf;color:#a3356b}.button{border:1px solid var(--line);background:white;color:var(--ink);padding:9px 14px;border-radius:6px;font-size:14px}.button.primary{background:var(--blue);color:white;border-color:var(--blue)}.button:hover{filter:brightness(.96)}.button:disabled{opacity:.5;cursor:default}.metrics{display:grid;grid-template-columns:repeat(4,1fr);gap:16px;margin-bottom:24px}.metric{padding:19px 22px;background:white;border:1px solid var(--line);border-radius:9px;position:relative;overflow:hidden}.metric:before{content:'';position:absolute;left:0;top:0;bottom:0;width:3px;background:var(--blue)}.metric:nth-child(2):before{background:var(--pink)}.metric:nth-child(3):before{background:var(--teal)}.metric:nth-child(4):before{background:var(--orange)}.metric label{font-size:13px;color:var(--muted)}.metric strong{display:block;font-size:28px;letter-spacing:-.7px;margin:4px 0}.metric small{font-size:12px;color:var(--muted)}.card{background:white;border:1px solid var(--line);border-radius:9px;margin-bottom:20px;padding:24px}.cardheader{display:flex;align-items:center;justify-content:space-between;gap:16px;margin-bottom:18px}.cardheader p{font-size:13px;color:var(--muted);margin-bottom:0}.searchrow{display:flex;gap:12px;align-items:stretch}.searchrow input{width:100%;border:1px solid #bfcade;border-radius:6px;padding:12px 15px;min-width:0;background:#fafbfe}.searchrow button{padding:12px 24px}.search-hint{display:flex;gap:8px;align-items:center;flex-wrap:wrap;margin-top:12px;color:var(--muted);font-size:13px}.chip{border:1px solid var(--line);padding:3px 9px;background:white;border-radius:4px;color:#465572;font-size:12px}.results{display:flex;gap:8px;flex-wrap:wrap;margin:15px 0 0}.results button.active{background:#eaf0ff;border-color:#91adee;color:#315dae}.tabs{display:flex;gap:24px;border-bottom:1px solid var(--line);margin:0 0 22px;overflow:auto}.tabs button{border:0;border-bottom:3px solid transparent;background:none;color:var(--muted);padding:13px 0;white-space:nowrap;font-size:14px}.tabs button.active{color:var(--blue);border-color:var(--blue);font-weight:650}.tabs button.co.active{color:var(--pink);border-color:var(--pink)}.proteinhead{display:flex;justify-content:space-between;align-items:center;gap:16px;margin:25px 0 8px}.proteinhead h2{font-size:23px}.proteinhead small{color:var(--muted);font-size:12px}.controls{display:flex;gap:10px;flex-wrap:wrap}.controls label{font-size:13px;color:var(--muted)}select{font-size:14px;padding:8px;border-radius:5px;border:1px solid var(--line);background:white;color:var(--ink)}.grid2{display:grid;grid-template-columns:1.1fr 1fr;gap:20px}.chart{width:100%;display:block;max-height:460px}.chart text{font-family:Arial,sans-serif;font-size:13px;fill:#647189}.chart .chart-label{fill:var(--ink);font-size:13px}.notice{background:#f7f9fe;border-left:3px solid #7895c8;padding:12px 16px;font-size:13px;color:#55627a;margin:17px 0}.notice.co{background:#fff7fb;border-color:var(--pink)}.tablewrap{overflow:auto}table{width:100%;border-collapse:collapse;font-size:14px;text-align:left;white-space:nowrap}th{background:#f5f7fb;color:#667389;font-size:12px;font-weight:600;padding:11px 13px;border-bottom:1px solid var(--line)}td{padding:12px 13px;border-bottom:1px solid #eef1f6}td small{display:block;font-size:12px;color:var(--muted)}.number{font-variant-numeric:tabular-nums;font-family:Arial,sans-serif;text-align:right}.dot{display:inline-block;width:7px;height:7px;background:#557fb8;border-radius:50%;margin-right:7px}.dot.co{background:var(--pink)}.empty{padding:38px;color:var(--muted);text-align:center;border:1px dashed #cdd6e5;border-radius:8px}.co-card{background:linear-gradient(120deg,#fff,#fff5fa);border-color:#ebcddd}.co-callout{display:flex;justify-content:space-between;align-items:center;gap:20px}.co-callout p{font-size:14px;color:var(--muted);max-width:680px}.categorygrid{display:grid;grid-template-columns:repeat(4,1fr);gap:14px;margin-bottom:22px}.category-card{background:white;border:1px solid var(--line);border-top:3px solid var(--blue);padding:18px;border-radius:7px}.category-card:last-child{border-top-color:var(--pink);background:#fff8fc}.category-card p{color:var(--muted);font-size:13px;min-height:44px}.category-card strong{font-size:23px}.legend{display:flex;gap:18px;font-size:12px;color:var(--muted);margin-top:12px}.legend i{display:inline-block;width:10px;height:10px;background:#067e75;margin-right:5px}.legend .missing{background:#e5eaf3}.heatmap{display:grid;gap:4px;grid-template-columns:180px repeat(8,minmax(45px,1fr));min-width:650px}.heatmap div{font-size:12px;padding:9px;text-align:center;border-radius:4px}.heatmap .label{text-align:left;padding-left:0}.heatmap .cell{color:white}.heatmap .none{background:#f0f3f8;color:#8c98a9}.method-content{max-width:900px}.method-content h2{margin:26px 0 10px}.method-content li{margin:9px 0;color:#4b5972;font-size:15px}.method-content code{font-size:13px;background:#eef2fa;padding:2px 5px;border-radius:3px}footer{display:flex;justify-content:space-between;gap:20px;border-top:1px solid var(--line);padding:24px 38px;font-size:12px;color:var(--muted)}#status{padding:70px;text-align:center}.co-flag{font-size:12px;color:#a6376d;display:inline-flex;align-items:center;gap:7px}.error{color:#af3457}.datasetbadge{font-size:12px;color:var(--muted)}.toolbar{display:flex;gap:12px;align-items:center;margin-bottom:18px;flex-wrap:wrap}
.card{overflow:auto}.chart{min-width:560px;max-height:none}.grid2>*{min-width:0}
@media(min-width:1600px){main{padding-top:42px}.card{padding:28px}.heading{margin-bottom:30px}}@media(max-width:1100px){.sidebar{width:205px;padding:28px 14px}.page{margin-left:205px}main{padding:28px 24px}.grid2{grid-template-columns:1fr}.metrics{grid-template-columns:repeat(2,1fr)}.categorygrid{grid-template-columns:repeat(2,1fr)}.topbar{padding:0 24px}.topnote{display:none}}@media(max-width:700px){.sidebar{position:static;width:100%;padding:15px 18px}.brand{font-size:25px}.brandmark{width:34px;height:37px}.sidebar nav{display:flex;gap:4px;overflow:auto;margin-top:13px}.navlabel,.sidebar-bottom{display:none}nav button{width:auto;white-space:nowrap;padding:8px 10px;font-size:13px}nav button span,nav b{display:none}.page{margin-left:0}.topbar{height:50px;padding:0 18px;font-size:12px}main{padding:24px 18px}h1{font-size:27px}.heading{align-items:flex-start}.heading>.badge{display:none}.metrics{gap:9px}.metric{padding:13px}.metric strong{font-size:25px}.card{padding:18px}.searchrow{gap:8px}.searchrow button{padding:10px 12px}.proteinhead,.co-callout{align-items:flex-start;flex-direction:column}.categorygrid{grid-template-columns:1fr 1fr}.cardheader{flex-wrap:wrap}footer{padding:20px 18px;flex-direction:column}.tabs{gap:18px}.subtitle{font-size:14px}}

.filterbar{display:flex;flex-wrap:wrap;gap:14px;padding:16px 18px;background:white;border:1px solid var(--line);border-radius:8px;margin:10px 0}.filterbar label{display:flex;flex-direction:column;gap:5px;font-size:13px;color:var(--muted);min-width:165px}.filterbar button{align-self:end}.querycard{border-top:3px solid var(--blue)}.inventory summary{cursor:pointer;font-weight:600;margin-bottom:16px}.protocol-layout{display:grid;grid-template-columns:285px minmax(0,1fr);gap:22px;align-items:start}.protocol-selector label{display:block;font-size:14px;margin-bottom:9px}.protocol-selector select{width:100%}.protocol-list{display:flex;flex-direction:column;gap:5px;margin:18px 0}.protocol-list button{background:white;border:1px solid transparent;text-align:left;padding:10px;border-radius:5px;font-size:14px;color:var(--ink)}.protocol-list button.active{background:#edf3ff;border-color:#ccdafa;color:#315caa}.protocol-list small{display:block;color:var(--muted);font-size:12px;margin-top:3px}.downloadlink{display:block;text-decoration:none;font-size:13px;text-align:center}.protocol-content h3{margin:25px 0 9px;font-size:18px}.protocol-content p{margin:12px 0;line-height:1.65}.protocol-content table{white-space:normal}.protocol-content td{vertical-align:top}.protocol-content .tablewrap{margin:20px 0}.protocol-content{overflow-wrap:anywhere}@media(max-width:1000px){.protocol-layout{grid-template-columns:1fr}.protocol-list{display:none}}@media(max-width:700px){.filterbar label{min-width:130px;flex:1}.filterbar select{width:100%}}

.overview-figure{margin:0 0 24px;padding:16px}.overview-trigger{display:block;width:100%;padding:0;border:0;background:white;cursor:zoom-in;border-radius:8px}.overview-trigger img{display:block;width:100%;height:auto}.overview-trigger:focus-visible{outline:3px solid #187fb5;outline-offset:4px}.overview-figure figcaption{text-align:center;color:#617089;font-size:14px;margin-top:12px}.overview-dialog{width:min(1400px,94vw);max-width:94vw;max-height:94vh;padding:16px;border:0;border-radius:12px;overflow:auto;background:#fff}.overview-dialog::backdrop{background:rgba(13,28,49,.8)}.overview-dialog form{position:sticky;top:0;display:flex;justify-content:flex-end;margin-bottom:12px}.overview-dialog img{display:block;width:100%;height:auto}